Anti-fibrotic Effects of Synthetic Oligodeoxynucleotide for TGF-β1 and Smad in an Animal Model of Liver Cirrhosis

• Main Authors: Jung-Yeon Kim (Author), Hyun-Jin An (Author), Woon-Hae Kim (Author), Mi-Gyeong Gwon (Author), Hyemin Gu (Author), Yoon-Yub Park (Author), Kwan-Kyu Park (Author)
• Format: Book
• Published: Elsevier, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver fibrosis is characterized by changes in tissue architecture and extracellular matrix composition. Liver fibrosis affects not only hepatocytes but also the non-parenchymal cells such as hepatic stellate cells (HSCs), which are essential for maintaining an intact liver structure and function. Tr...