Discovery of an orally effective double-stapled peptide for reducing ovariectomy-induced bone loss in mice

Stapled peptides with significantly enhanced pharmacological profiles have emerged as promising therapeutic molecules due to their remarkable resistance to proteolysis and performance to penetrate cells. The all-hydrocarbon peptide stapling technique has already widely adopted with great success, yi...

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Main Authors: Wei Cong (Author), Huaxing Shen (Author), Xiufei Liao (Author), Mengjun Zheng (Author), Xianglong Kong (Author), Zhe Wang (Author), Si Chen (Author), Yulei Li (Author), Honggang Hu (Author), Xiang Li (Author)
Format: Book
Published: Elsevier, 2023-09-01T00:00:00Z.
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