Study of the impact of different salts on the intrinsic dissolution rate of pharmaceutical compounds

The intrinsic dissolution rate (IDR) of a free base and its four salts were investigated with the aim of selecting the salt with the best dissolution performance. IDRs were measured using the Sirius inForm platform with quantitation by in-situ UV spectroscopy. Results showed that the hydrochloride s...

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Autori principali: Karl Box (Autore), Rebeca Ruiz (Autore), Breeze Outhwaite (Autore), Sam Lee (Autore)
Natura: Libro
Pubblicazione: University of Huddersfield Press, 2017-12-01T00:00:00Z.
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