Kaurenoic Acid Possesses Leishmanicidal Activity by Triggering a NLRP12/IL-1β/cNOS/NO Pathway

• मुख्य लेखकों: Milena Menegazzo Miranda (लेखक), Carolina Panis (लेखक), Suelen Santos da Silva (लेखक), Juliana Aparecida Macri (लेखक), Natalia Yoshie Kawakami (लेखक), Thiago Hideki Hayashida (लेखक), Tiago Bervelieri Madeira (लेखक), Vinicius Ricardo Acquaro (लेखक), Suzana Lucy Nixdorf (लेखक), Luciana Pizzatti (लेखक), Sérgio Ricardo Ambrósio (लेखक), Rubens Cecchini (लेखक), Nilton Syogo Arakawa (लेखक), Waldiceu Aparecido Verri (लेखक), Ivete Conchon Costa (लेखक), Wander Rogério Pavanelli (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2015-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Leishmania amazonensis (L. amazonensis) infection can cause severe local and diffuse injuries in humans, a condition clinically known as American cutaneous leishmaniasis (ACL). Currently, the therapeutic approach for ACL is based on Glucantime, which shows high toxicity and poor effectiveness. There...