Structure-Guide Design and Optimization of Potential Druglikeness Inhibitors for TGFβRI with the Pyrrolopyrimidine Scaffold

Among all types of TGFβ signal blockers, small molecule kinase inhibitors (SMKIs) have attracted wide attention due to their economical production, obvious stability, and ease of oral administration. Nevertheless, SMKIs of TGFβRItypically have low druggability so there are none on the market. In thi...

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Main Authors: Dan Meng (Author), Jiali Xie (Author), Yihao Li (Author), Ruoyu Li (Author), Hui Zhou (Author), Ping Deng (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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