Neuroprotective effects of ellagic acid on cuprizone-induced acute demyelination through limitation of microgliosis, adjustment of CXCL12/IL-17/IL-11 axis and restriction of mature oligodendrocytes apoptosis

• Main Authors: Nima Sanadgol (Author), Fereshteh Golab (Author), Zakiyeh Tashakkor (Author), Nooshin Taki (Author), Samira Moradi Kouchi (Author), Ali Mostafaie (Author), Mehdi Mehdizadeh (Author), Mohammad Abdollahi (Author), Ghorban Taghizadeh (Author), Mohammad Sharifzadeh (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context: Ellagic acid (EA) is a natural phenol antioxidant with various therapeutic activities. However, the efficacy of EA has not been examined in neuropathologic conditions. Objective: In vivo neuroprotective effects of EA on cuprizone (cup)-induced demyelination were evaluated. Material and meth...