Carajurin Induces Apoptosis in <i>Leishmania amazonensis</i> Promastigotes through Reactive Oxygen Species Production and Mitochondrial Dysfunction

• 主要な著者: João Victor Silva-Silva (著者), Carla J. Moragas-Tellis (著者), Maria S. S. Chagas (著者), Paulo Victor R. Souza (著者), Davyson L. Moreira (著者), Daiana J. Hardoim (著者), Noemi N. Taniwaki (著者), Vanessa F. A. Costa (著者), Alvaro L. Bertho (著者), Daniela Brondani (著者), Eduardo Zapp (著者), Aldo Sena de Oliveira (著者), Kátia S. Calabrese (著者), Maria D. Behrens (著者), Fernando Almeida-Souza (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Carajurin is the main constituent of <i>Arrabidaea chica</i> species with reported anti-<i>Leishmania</i> activity. However, its mechanism of action has not been described. This study investigated the mechanisms of action of carajurin against promastigote forms of <i>Le...