The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors

• मुख्य लेखकों: Richard G. W. Proudman (लेखक), Jillian G. Baker (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2021-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Highly selective drugs offer a way to minimize side‐effects. For agonist ligands, this could be through highly selective affinity or highly selective efficacy, but this requires careful measurements of intrinsic efficacy. The α1‐adrenoceptors are important clinical targets, and α1‐agonists...