Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on <i>Haemonchus contortus</i> Adults and Eggs, and Their Hepatotoxicity and Biotransformation

• Main Authors: Markéta Zajíčková (Author), Lukáš Prchal (Author), Ivan Vokřál (Author), Linh Thuy Nguyen (Author), Thomas Kurz (Author), Robin Gasser (Author), Klára Bednářová (Author), Magdalena Mičundová (Author), Beate Lungerich (Author), Oliver Michel (Author), Lenka Skálová (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As a widely distributed parasitic nematode of ruminants, <i>Haemonchus contortus</i> has become resistant to most anthelmintic classes, there has been a major demand for new compounds against <i>H. contortus</i> and related nematodes. Recent phenotypic screening has revealed...