Anti-Inflammatory, Antioxidant, and WAT/BAT-Conversion Stimulation Induced by Novel PPAR Ligands: Results from Ex Vivo and In Vitro Studies

• Main Authors: Lucia Recinella (Author), Barbara De Filippis (Author), Maria Loreta Libero (Author), Alessandra Ammazzalorso (Author), Annalisa Chiavaroli (Author), Giustino Orlando (Author), Claudio Ferrante (Author), Letizia Giampietro (Author), Serena Veschi (Author), Alessandro Cama (Author), Federica Mannino (Author), Irene Gasparo (Author), Alessandra Bitto (Author), Rosa Amoroso (Author), Luigi Brunetti (Author), Sheila Leone (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activation of peroxisome proliferator-activated receptors (PPARs) not only regulates multiple metabolic pathways, but mediates various biological effects related to inflammation and oxidative stress. We investigated the effects of four new PPAR ligands containing a fibrate scaffold-the PPAR agonists...