Antiallodynic Action of 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methyoxyphenyl)-4-piperidinol (NNC05-2090), a Betaine/GABA Transporter Inhibitor

• Main Authors: Ayako Jinzenji (Author), Chiharu Sogawa (Author), Takuya Miyawaki (Author), Xue-fang Wen (Author), Dan Yi (Author), Kazumi Ohyama (Author), Shigeo Kitayama (Author), Norio Sogawa (Author), Katsuya Morita (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: The GABAergic system in the spinal cord has been shown to participate in neuropathic pain in various animal models. GABA transporters (GATs) play a role in controlling the synaptic clearance of GABA; however, their role in neuropathic pain remains unclear. In the present study, we compare...