lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration

• Main Authors: Yanyun Zhao (Author), Zhaojin Yu (Author), Rong Ma (Author), Yifan Zhang (Author), Lin Zhao (Author), Yuanyuan Yan (Author), Xuemei Lv (Author), Liwen Zhang (Author), Panpan Su (Author), Jia Bi (Author), Hong Xu (Author), Miao He (Author), Minjie Wei (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The phenotypic switch in tumor-associated macrophages (TAMs) mediates immunity escape of cancer. However, the underlying mechanisms in the TAM phenotypic switch have not been systematically elucidated. In this study, long noncoding RNA (lncRNA)-Xist, CCAAT/enhancer-binding protein (C/EBP)α, and Krup...