USP7: Novel Drug Target in Cancer Therapy
Ubiquitin specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUB) that erases ubiquitin and protects substrate protein from degradation. Full activity of USP7 requires the C-terminal Ub-like domains fold back onto the catalytic domain, allowing the remodeling of the active site to a...
Saved in:
Main Authors: | Zhiru Wang (Author), Wenting Kang (Author), Yinghua You (Author), Jingru Pang (Author), Hongmei Ren (Author), Zhenhe Suo (Author), Hongmin Liu (Author), Yichao Zheng (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2019-04-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Abrogation of USP7 is an alternative strategy to downregulate PD-L1 and sensitize gastric cancer cells to T cells killing
by: Zhiru Wang, et al.
Published: (2021) -
Exploration of 5-cyano-6-phenylpyrimidin derivatives containing an 1,2,3-triazole moiety as potent FAD-based LSD1 inhibitors
by: Liying Ma, et al.
Published: (2020) -
Development and Evaluation of Multifunctional Poly(Lactic-co-glycolic acid) Nanoparticles Embedded in Carboxymethyl β-Glucan Porous Microcapsules as a Novel Drug Delivery System for Gefitinib
by: Xiaonan Li, et al.
Published: (2019) -
Public Interest in Cosmetic Surgical and Minimally Invasive Plastic Procedures During the COVID-19 Pandemic: Infodemiology Study of Twitter Data
by: Liu, Wenhui, et al.
Published: (2021) -
Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer
by: Ying Liu, et al.
Published: (2021)