Synthesis of Novel 1,3,4-Oxadiazole-Derived <i>α</i>-Aminophosphonates/<i>α</i>-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian Coronavirus Infectious Bronchitis Virus

Synthesis of Novel 1,3,4-Oxadiazole-Derived <i>α</i>-Aminophosphonates/<i>α</i>-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian Coronavirus Infectious Bronchitis Virus

An efficient and simple approach has been developed for the synthesis of eight dialkyl/aryl[(5-phenyl-1,3,4-oxadiazol-2-ylamino)(aryl)methyl]phosphonates through the Pudovik-type reaction of dialkyl/arylphosphite with imines, obtained from 5-phenyl-1,3,4-oxadiazol-2-amine and aromatic aldehydes, und...

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Main Authors: Shaima Hkiri (Author), Marwa Mekni-Toujani (Author), Elvan Üstün (Author), Karim Hosni (Author), Abdeljelil Ghram (Author), Soufiane Touil (Author), Ali Samarat (Author), David Sémeril (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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