Synthesis of Novel 1,3,4-Oxadiazole-Derived <i>α</i>-Aminophosphonates/<i>α</i>-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian Coronavirus Infectious Bronchitis Virus

• 主要な著者: Shaima Hkiri (著者), Marwa Mekni-Toujani (著者), Elvan Üstün (著者), Karim Hosni (著者), Abdeljelil Ghram (著者), Soufiane Touil (著者), Ali Samarat (著者), David Sémeril (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

An efficient and simple approach has been developed for the synthesis of eight dialkyl/aryl[(5-phenyl-1,3,4-oxadiazol-2-ylamino)(aryl)methyl]phosphonates through the Pudovik-type reaction of dialkyl/arylphosphite with imines, obtained from 5-phenyl-1,3,4-oxadiazol-2-amine and aromatic aldehydes, und...