Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients

Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients

<p>Abstract</p> <p>Background</p> <p>Sulfamethoxazole (SMX) is a commonly used antibiotic for prevention of infectious diseases associated with HIV/AIDS and immune-compromised states. SMX-induced hypersensitivity is an idiosyncratic cutaneous drug reaction with genetic...

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Main Authors: Wang Danxin (Author), Curtis Amanda (Author), Papp Audrey C (Author), Koletar Susan L (Author), Para Michael F (Author)
Format: Book
Published: BMC, 2012-07-01T00:00:00Z.
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