Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress

• Main Authors: Raquel González-Blázquez (Author), Beatriz Somoza (Author), Marta Gil-Ortega (Author), Miriam Martín Ramos (Author), David Ramiro-Cortijo (Author), Elena Vega-Martín (Author), Angela Schulz (Author), Luis Miguel Ruilope (Author), Peter Kolkhof (Author), Reinhold Kreutz (Author), María S. Fernández-Alfonso (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Albuminuria is an early marker of renovascular damage associated to an increase in oxidative stress. The Munich Wistar Frömter (MWF) rat is a model of chronic kidney disease (CKD), which exhibits endothelial dysfunction associated to low nitric oxide availability. We hypothesize that the new highly...