Berberine Targets PKM2 to Activate the t-PA-Induced Fibrinolytic System and Improves Thrombosis

• Main Authors: Zeqi Sun (Author), Tong Zhao (Author), Xue Bai (Author), Huimin Li (Author), Jin Gao (Author), Yutong Hao (Author), Yiyang Li (Author), Yanli Xie (Author), Ange Hu (Author), Qiang Huang (Author), Xin Liu (Author), Yong Zhang (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Arterial thrombosis, a condition in which thrombi form in arteries, can lead to various acute cardiovascular diseases and impact the quality of life and survival of patients. Berberine (BBR), a quaternary ammonium alkaloid, has been shown to treat these diseases. However, further explora...