Novel Regioselective Synthesis of 1,3,4,5-Tetrasubstituted Pyrazoles and Biochemical Valuation on F<sub>1</sub>F<sub>O</sub>-ATPase and Mitochondrial Permeability Transition Pore Formation
An efficient, eco-compatible, and very cheap method for the construction of fully substituted pyrazoles (Pzs) via eliminative nitrilimine-alkene 1,3-dipolar cycloaddition (ENAC) reaction was developed in excellent yield and high regioselectivity. Enaminones and nitrilimines generated in situ were se...
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MDPI AG,
2023-02-01T00:00:00Z.
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A1234.567 |
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