A Cystine-Rich Whey Supplement (Immunocal®) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

• मुख्य लेखकों: Erika K. Ross (लेखक), Aimee N. Winter (लेखक), Heather M. Wilkins (लेखक), Whitney A. Sumner (लेखक), Nathan Duval (लेखक), David Patterson (लेखक), Daniel A. Linseman (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2014-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Depletion of the endogenous antioxidant, glutathione (GSH), underlies progression of the devastating neurodegenerative disease, amyotrophic lateral sclerosis (ALS). Thus, strategies aimed at elevating GSH may yield new therapeutics for ALS. Here, we investigated the effects of a unique non-denatured...