Is the current therapeutic dosage of nadroparin adequate for neonates and infants under 8 months with thromboembolic disease? a population pharmacokinetic study from a national children's medical center

Objectives: Nadroparin, a low-molecular-weight-heparin is commonly used off-label in neonates and infants for thromboembolic events prevention. However, the recommended dosing regimen often fails to achieve therapeutic target ranges. This study aimed to develop a population pharmacokinetic (PK) mode...

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Main Authors: Yewei Chen (Author), Jianger Lan (Author), Lin Zhu (Author), Min Dong (Author), Yi Wang (Author), Zhiping Li (Author)
Format: Book
Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
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