α-Glucosidase inhibitory activity and cytotoxic effects of some cyclic urea and carbamate derivatives

• Main Authors: Jelena B. Popović-Djordjević (Author), Ivana I. Jevtić (Author), Nadja Dj Grozdanić (Author), Sandra B. Šegan (Author), Mario V. Zlatović (Author), Milovan D. Ivanović (Author), Tatjana P. Stanojković (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The inhibitory activities of selected cyclic urea and carbamate derivatives (1-13) toward α-glucosidase (α-Gls) in in vitro assay were examined in this study. All examined compounds showed higher inhibitory activity (IC50) against α-Gls compared to standard antidiabetic drug acarbose. The most poten...