Topical Pioglitazone Nanoformulation for the Treatment of Atopic Dermatitis: Design, Characterization and Efficacy in Hairless Mouse Model

• Main Authors: Lupe Carolina Espinoza (Author), Rodrigo Vera-García (Author), Marcelle Silva-Abreu (Author), Òscar Domènech (Author), Josefa Badia (Author), María J. Rodríguez-Lagunas (Author), Beatriz Clares (Author), Ana Cristina Calpena (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pioglitazone (PGZ) is a drug used to treat type 2 diabetes mellitus that has been reported to show additional therapeutic activities on diverse inflammatory parameters. The aim of this study was to optimize a topical PGZ-loaded nanoemulsion (PGZ-NE) in order to evaluate its effectiveness for treatin...