Persistent Unresolved Inflammation in the Mecp2-308 Female Mutated Mouse Model of Rett Syndrome

• Main Authors: Alessio Cortelazzo (Author), Claudio De Felice (Author), Bianca De Filippis (Author), Laura Ricceri (Author), Giovanni Laviola (Author), Silvia Leoncini (Author), Cinzia Signorini (Author), Monica Pescaglini (Author), Roberto Guerranti (Author), Anna Maria Timperio (Author), Lello Zolla (Author), Lucia Ciccoli (Author), Joussef Hayek (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rett syndrome (RTT) is a rare neurodevelopmental disorder usually caused by mutations in the X-linked gene methyl-CpG-binding protein 2 (MECP2). Several Mecp2 mutant mouse lines have been developed recapitulating part of the clinical features. In particular, Mecp2-308 female heterozygous mice, beari...