Chrysin Protects Rat Kidney from Paracetamol-Induced Oxidative Stress, Inflammation, Apoptosis, and Autophagy: A Multi-Biomarker Approach

• Główni autorzy: Fatih Mehmet Kandemir (Autor), Sefa Kucukler (Autor), Eyup Eldutar (Autor), Cuneyt Caglayan (Autor), İlhami Gülçin (Autor)
• Format: Książka
• Wydane: MDPI AG, 2017-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Paracetamol (PC) is a safe analgesic and antipyretic drug at therapeutic doses, and it is widely used in clinics. However, at high doses, it can induce hepatotoxicity and nephrotoxicity. Chrysin (CR) is a natural flavonoid that has biological activities that include being an antioxidant, an anti-inf...