Validation of chromogenic in situ hybridization reactions for DNA and RNA detection in formalin-fixed paraffin-embedded tissue

• Main Authors: Raquel L. Monteiro (Author), Daniela S. Damaceno (Author), Lidia M. Kimura (Author), Cinthya S. Cirqueira (Author), Juliana M. Guerra (Author), Leonardo José T. Araújo (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Introduction: Chromogenic in situ hybridization (CISH) is used alternatively to the traditional immunohistochemical methods for the diagnosis of infectious diseases in formalin-fixed paraffin-embedded samples, since it presents high sensitivity and specificity. This type of sample undergoes...