Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes

• Main Authors: Jingya Lyu (Author), Hitomi Imachi (Author), Kensaku Fukunaga (Author), Seisuke Sato (Author), Toshihiro Kobayashi (Author), Tao Dong (Author), Takanobu Saheki (Author), Mari Matsumoto (Author), Hisakazu Iwama (Author), Huanxiang Zhang (Author), Koji Murao (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1) influences hepatic cholesterol transportation. Accumulation of hepatic cholesterol leads to fatty liver disease, which is improved by glucagon-like peptide 1 (GLP-1) in diabetes. Therefore, we analyzed the molecular mech...