Scribble basal polarity acquisition in RPE cells and its mislocalization in a pathological AMD-like model

• Main Authors: Alicia Segurado (Author), Alba Rodríguez-Carrillo (Author), Bárbara Castellanos (Author), Emiliano Hernández-Galilea (Author), Almudena Velasco (Author), Concepción Lillo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Apicobasal polarity is a hallmark of retinal pigment epithelium cells and is required to perform their functions; however, the precise roles of the different proteins that execute polarity are still poorly understood. Here, we have studied the expression and location of Scribble, the core member of...