A pathologist-in-the-loop IHC antibody test selection using the entropy-based probabilistic method

• Main Authors: Dmitriy Shin (Author), Gerald Arthur (Author), Charles Caldwell (Author), Mihail Popescu (Author), Marius Petruc (Author), Alberto Diaz-Arias (Author), Chi-Ren Shyu (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Immunohistochemistry (IHC) is an important tool to identify and quantify expression of certain proteins (antigens) to gain insights into the molecular processes in a diseased tissue. However, it is a challenge for pathologists to remember the discriminative characteristics of the growing...