Pharmacokinetics and Pharmacodynamics of (S)-Ketoprofen Co-Administered with Caffeine: A Preclinical Study in Arthritic Rats

The purpose of the present study was to determine whether caffeine modifies the pharmacokinetics and pharmacodynamics of (S)-ketoprofen following oral administration in a gout-type pain model. 3.2 mg/kg of (S)-ketoprofen alone and combined with 17.8 mg/kg of caffeine were administered to Wistar rats...

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Bibliographic Details
Main Authors: Raúl Medina-López (Author), Nancy Vara-Gama (Author), Olivia Soria-Arteche (Author), Luis A. Moreno-Rocha (Author), Francisco J. López-Muñoz (Author)
Format: Book
Published: MDPI AG, 2018-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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