Analysis of riociguat and desmethyl riociguat by UPLC-MS/MS and its interaction with quercetin

Riociguat, an orally soluble guanylate cyclase (sGC)-promoting drug, is mainly used in the clinical treatment of pulmonary hypertension (PH). In this study, a novel ultra-performance liquid chromatography-tandem mass spectrometry method was developed to quantify the concentrations of riociguat and i...

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Main Authors: Qingqing Li (Author), Xiaohai Chen (Author), Siping Zhang (Author), Wanshu Li (Author), Hangjuan Lin (Author)
Format: Book
Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
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