Analysis of riociguat and desmethyl riociguat by UPLC-MS/MS and its interaction with quercetin

• Asıl Yazarlar: Qingqing Li (Yazar), Xiaohai Chen (Yazar), Siping Zhang (Yazar), Wanshu Li (Yazar), Hangjuan Lin (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Riociguat, an orally soluble guanylate cyclase (sGC)-promoting drug, is mainly used in the clinical treatment of pulmonary hypertension (PH). In this study, a novel ultra-performance liquid chromatography-tandem mass spectrometry method was developed to quantify the concentrations of riociguat and i...