A fully automatic tool for development of population pharmacokinetic models

• Main Authors: Xiaomei Chen (Author), Rikard Nordgren (Author), Stella Belin (Author), Alzahra Hamdan (Author), Shijun Wang (Author), Tianwu Yang (Author), Zhe Huang (Author), Simon J. Carter (Author), Simon Buatois (Author), João A. Abrantes (Author), Andrew C. Hooker (Author), Mats O. Karlsson (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Population pharmacokinetic (PK) models are widely used to inform drug development by pharmaceutical companies and facilitate drug evaluation by regulatory agencies. Developing a population PK model is a multi‐step, challenging, and time‐consuming process involving iterative manual model fit...