Characterization of Mechanical Allodynia and Skin Innervation in a Mouse Model of Type-2 Diabetes Induced by Cafeteria-Style Diet and Low-Doses of Streptozotocin

• Main Authors: Gabriela Castañeda-Corral (Author), Norma B. Velázquez-Salazar (Author), Arisai Martínez-Martínez (Author), Juanita N. Taboada-Serrano (Author), Pablo N. Núñez-Aragón (Author), Laura González-Palomares (Author), Rosa Issel Acosta-González (Author), Vera L. Petricevich (Author), Juan José Acevedo-Fernández (Author), Sergio Montes (Author), Juan Miguel Jiménez-Andrade (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Painful distal symmetrical polyneuropathy (DPN) is a frequent complication of type-2 diabetes mellitus (T2DM) that commonly presents as neuropathic pain and loss of skin nerve fibers. However, there are limited therapies to effectively treat DPN and many of the current animal models of T...