N‐Palmitoylglycine and other N‐acylamides activate the lipid receptor G2A/GPR132

• मुख्य लेखकों: James R. Foster (लेखक), Shohta Ueno (लेखक), Mao Xiang Chen (लेखक), Jenni Harvey (लेखक), Simon J. Dowell (लेखक), Andrew J. Irving (लेखक), Andrew J. Brown (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2019-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract The G‐protein‐coupled receptor GPR132, also known as G2A, is activated by 9‐hydroxyoctadecadienoic acid (9‐HODE) and other oxidized fatty acids. Other suggested GPR132 agonists including lysophosphatidylcholine (LPC) have not been readily reproduced. Here, we identify N‐acylamides in partic...