N‐Palmitoylglycine and other N‐acylamides activate the lipid receptor G2A/GPR132

• Päätekijät: James R. Foster (Tekijä), Shohta Ueno (Tekijä), Mao Xiang Chen (Tekijä), Jenni Harvey (Tekijä), Simon J. Dowell (Tekijä), Andrew J. Irving (Tekijä), Andrew J. Brown (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2019-12-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract The G‐protein‐coupled receptor GPR132, also known as G2A, is activated by 9‐hydroxyoctadecadienoic acid (9‐HODE) and other oxidized fatty acids. Other suggested GPR132 agonists including lysophosphatidylcholine (LPC) have not been readily reproduced. Here, we identify N‐acylamides in partic...