Pathogen- and Host-Directed Antileishmanial Effects Mediated by Polyhexanide (PHMB).

• Main Authors: Rebuma Firdessa (Author), Liam Good (Author), Maria Cecilia Amstalden (Author), Kantaraja Chindera (Author), Nor Fadhilah Kamaruzzaman (Author), Martina Schultheis (Author), Bianca Röger (Author), Nina Hecht (Author), Tobias A Oelschlaeger (Author), Lorenz Meinel (Author), Tessa Lühmann (Author), Heidrun Moll (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Cutaneous leishmaniasis (CL) is a neglected tropical disease caused by protozoan parasites of the genus Leishmania. CL causes enormous suffering in many countries worldwide. There is no licensed vaccine against CL, and the chemotherapy options show limited efficacy and high toxicity. Loca...