Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography.
Chagas disease, caused by Trypanosoma cruzi, affects millions of people in South America and no satisfactory therapy exists, especially for its life threatening chronic phase. We targeted the Proline Racemase of T. cruzi, which is present in all stages of the parasite life cycle, to discover new inh...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2018-10-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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