N-Acetyl-l-Cysteine Inhibits Marble-Burying Behavior in Mice

• Main Authors: Nobuaki Egashira (Author), Atsunori Shirakawa (Author), Moe Abe (Author), Tomiko Niki (Author), Kenichi Mishima (Author), Katsunori Iwasaki (Author), Ryozo Oishi (Author), Michihiro Fujiwara (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, we examined the effect of N-acetyl-l-cysteine (NAC), a glutamate-modulating agent, on marble-burying behavior in mice. Fluvoxamine (30 mg/kg, p.o.) and mirtazapine (3 mg/kg, i.p.) significantly inhibited marble-burying behavior without affecting locomotor activity. Similarity,...