Preparation and Characterization of Amino Acids-Based Trimethoprim Salts

Trimethoprim (TMP) is a dihydrofolate reductase (DHFR) inhibitor which prevents the conversion of dihydrofolic acid into tetrahydrofolic acid, resulting in the depletion of the latter and leading to bacterial death. Oral bioavailability of TMP is hindered by both its low solubility and low permeabil...

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Main Authors: Afzal R. Mohammed (Author), Tony Worthington (Author), Peter Hanson (Author), Amr ElShaer (Author), Peter Lambert (Author)
Format: Book
Published: MDPI AG, 2012-02-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
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