Molecular Connectivity Predefines Polypharmacology: Aliphatic Rings, Chirality, and sp3 Centers Enhance Target Selectivity

Dark chemical matter compounds are small molecules that have been recently identified as highly potent and selective hits. For this reason, they constitute a promising class of possible candidates in the process of drug discovery and raise the interest of the scientific community. To this purpose, W...

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Bibliographic Details
Main Authors: Stefania Monteleone (Author), Julian E. Fuchs (Author), Klaus R. Liedl (Author)
Format: Book
Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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