Analytical Quality by Design (AQbD) Approach to the Development of In Vitro Release Test for Topical Hydrogel

• Main Authors: Réka Szoleczky (Author), Mária Budai-Szűcs (Author), Erzsébet Csányi (Author), Szilvia Berkó (Author), Péter Tonka-Nagy (Author), Ildikó Csóka (Author), Anita Kovács (Author)
• 格式: 图书
• 出版: MDPI AG, 2022-03-01T00:00:00Z.
• 主题: article
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The aim of our study was to adapt the analytical quality by design (AQbD) approach to design an effective in vitro release test method using USP apparatus IV with a semi-solid adapter (SSA) for diclofenac sodium hydrogel. The analytical target profile (ATP) of the in vitro release test and ultra-hig...