CYP450 Genotype-Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting

• Автори: Kuntheavy Ing Lorenzini (Автор), Jules Desmeules (Автор), Victoria Rollason (Автор), Stéphane Bertin (Автор), Marie Besson (Автор), Youssef Daali (Автор), Caroline F. Samer (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Pharmacokinetic variability is a major source of differences in drug response and can be due to genetic variants and/or drug-drug interactions. Cytochromes P450 are among the most studied enzymes from a pharmacokinetic point of view. Their activity can be measured by phenotyping, and/or predicted by...