CYP450 Genotype-Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting

• Main Authors: Kuntheavy Ing Lorenzini (Author), Jules Desmeules (Author), Victoria Rollason (Author), Stéphane Bertin (Author), Marie Besson (Author), Youssef Daali (Author), Caroline F. Samer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacokinetic variability is a major source of differences in drug response and can be due to genetic variants and/or drug-drug interactions. Cytochromes P450 are among the most studied enzymes from a pharmacokinetic point of view. Their activity can be measured by phenotyping, and/or predicted by...