Overexpression of ABCC2 and NF-Κβ/p65 with Reduction in Cisplatin and 4OH-Tamoxifen Sensitivity in MCF-7 Breast Cancer Cells: The Influence of TNF-α

• Главные авторы: Nafiseh Sadat Alamolhodaei (Автор), Hatam Rashidpour (Автор), Melika Ehtesham gharaee (Автор), Javad Behravan (Автор), Fatemeh Mosaffa (Автор)
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• Опубликовано: Tabriz University of Medical Sciences, 2020-06-01T00:00:00Z.
• Предметы: article
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Background: TNF-α, as a pro-inflammatory cytokine in the tumor microenvironment is able to regulate the expression and function of various ATP binding cassette (ABC) transporters involved in clinical drug resistance and among them, ABCC2 transporter is represented to contribute to cancer multidrug r...