Hyperinflammation in Two Severe Acute Respiratory Syndrome Coronavirus 2-Infected Adolescents Successfully Treated With the Interleukin-1 Inhibitor Anakinra and Glucocorticoids

• Main Authors: Francesca I. Calò Carducci (Author), Maria Antonietta De Ioris (Author), Chiara Agrati (Author), Rita Carsetti (Author), Daniela Perrotta (Author), Patrizia D'Argenio (Author), Fabrizio De Benedetti (Author), Stefania Notari (Author), Paolo Rossi (Author), Andrea Campana (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In severe acute respiratory syndrome-related coronavirus (SARS-CoV-2) critically ill adults, hyperinflammation plays a key role in disease progression. The clinical manifestations of SARS-CoV-2 infection among children are much less severe compared with adult patients and usually associa...