Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis

• Egile Nagusiak: Hei-Jen Huang (Egilea), Jie-Ling Chen (Egilea), Jian-Fu Liao (Egilea), Yu-Hsin Chen (Egilea), Min-Wei Chieu (Egilea), Ya-Yun Ke (Egilea), Chih-Chieh Hsu (Egilea), Ying-Chieh Tsai (Egilea), Hsiu Mei Hsieh-Li (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2021-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background According to recent evidence, psychobiotics exert beneficial effects on central nervous system-related diseases, such as mental disorders. Lactobacillus plantarum PS128 (PS128), a novel psychobiotic strain, improves motor function, depression, and anxiety behaviors. However, the...