Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis

• Main Authors: Hei-Jen Huang (Author), Jie-Ling Chen (Author), Jian-Fu Liao (Author), Yu-Hsin Chen (Author), Min-Wei Chieu (Author), Ya-Yun Ke (Author), Chih-Chieh Hsu (Author), Ying-Chieh Tsai (Author), Hsiu Mei Hsieh-Li (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background According to recent evidence, psychobiotics exert beneficial effects on central nervous system-related diseases, such as mental disorders. Lactobacillus plantarum PS128 (PS128), a novel psychobiotic strain, improves motor function, depression, and anxiety behaviors. However, the...