COVID-19 and children with Down syndrome: is there any real reason to worry? Two case reports with severe course

• Main Authors: Ahmad Kantar (Author), Angelo Mazza (Author), Ezio Bonanomi (Author), Marta Odoni (Author), Manuela Seminara (Author), Ilaria Dalla Verde (Author), Camillo Lovati (Author), Stefania Bolognini (Author), Lorenzo D'Antiga (Author)
• Format: Book
• Published: BMC, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Down syndrome (DS) is characterized by a series of immune dysregulations, of which interferon hyperreactivity is important, as it is responsible for surging antiviral responses and the possible initiation of an amplified cytokine storm. This biological condition is attributed to...