Yokukansankachimpihange, a traditional Japanese (Kampo) medicine, enhances the adaptation to circadian rhythm disruption by increasing endogenous melatonin levels

• Main Authors: Sachiko Imamura (Author), Masahiro Tabuchi (Author), Hiroaki Oizumi (Author), Toshiyuki Ueki (Author), Yuji Omiya (Author), Yasushi Ikarashi (Author), Kazushige Mizoguchi (Author)
• Format: Book
• Published: Elsevier, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The traditional Japanese (Kampo) medicines yokukansan (YKS) and yokukansankachimpihange (YKSCH) have similar formulas and the same indications. In animals or cultured cells, the neuropharmacological actions of YKS are sometimes more beneficial than those of YKSCH. Since both drugs are used to treat...