Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes

• Main Authors: Celedón Juan C (Author), Soto-Quirós Manuel (Author), Avila Lydiana (Author), Lazarus Ross (Author), Himes Blanca E (Author), Lasky-Su Jessica (Author), Zhou Xiaobo (Author), Lange Nancy E (Author), Hawrylowicz Catherine M (Author), Raby Benjamin A (Author), Litonjua Augusto A (Author)
• Format: Book
• Published: BMC, 2011-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Prior studies suggest a role for a variant (rs5743836) in the promoter of toll-like receptor 9 (TLR9) in asthma and other inflammatory diseases. We performed detailed genetic association studies of the functional variant rs5743836 wi...