Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes

• Hoofdauteurs: Celedón Juan C (Auteur), Soto-Quirós Manuel (Auteur), Avila Lydiana (Auteur), Lazarus Ross (Auteur), Himes Blanca E (Auteur), Lasky-Su Jessica (Auteur), Zhou Xiaobo (Auteur), Lange Nancy E (Auteur), Hawrylowicz Catherine M (Auteur), Raby Benjamin A (Auteur), Litonjua Augusto A (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2011-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Prior studies suggest a role for a variant (rs5743836) in the promoter of toll-like receptor 9 (TLR9) in asthma and other inflammatory diseases. We performed detailed genetic association studies of the functional variant rs5743836 wi...