Population Pharmacokinetic Model of Linezolid and Probability of Target Attainment in Patients with COVID-19-Associated Acute Respiratory Distress Syndrome on Veno-Venous Extracorporeal Membrane Oxygenation-A Step toward Correct Dosing

• Main Authors: Dragana Milaković (Author), Tijana Kovačević (Author), Pedja Kovačević (Author), Vedrana Barišić (Author), Sanja Avram (Author), Saša Dragić (Author), Biljana Zlojutro (Author), Danica Momčičević (Author), Branislava Miljković (Author), Katarina Vučićević (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During veno-venous extracorporeal membrane oxygenation (vv ECMO) therapy, antimicrobial drugs are frequently used, and appropriate dosing is challenging due to there being limited data to support the dosage. Linezolid is effective against multidrug-resistant Gram-positive pathogens frequently isolat...