β-Cyclodextrin metal-organic framework as a green carrier to improve the dissolution, bioavailability, and liver protective effect of luteolin

• Egile Nagusiak: Dan Yang (Egilea), Min Zhao (Egilea), Yihe Huang (Egilea), Liwen Chen (Egilea), Jiqin Fang (Egilea), Jiaonan Liu (Egilea), Miao Wang (Egilea), Chunjie Zhao (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The incidence of acetaminophen-induced liver injury has increased, but effective prevention methods are limited. Although luteolin has hepatoprotective activity, its low solubility and bioavailability limit its applications. Cyclodextrin metal-organic frameworks (CD-MOFs) possess 3D-network structur...