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Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis

A human artificial chromosome (HAC) is maintained as an episome within a cell and avoids random integration into the host genome. It can transfer multiple and/or large transgenes along with their regulatory elements thereby resembling native chromosomes. Using this HAC system, we established mesench...

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Bibliografische gegevens
Hoofdauteurs:	Yasuhiro Watanabe (Auteur), Yasuhiro Kazuki (Auteur), Kanako Kazuki (Auteur), Mitsutaka Ebiki (Auteur), Mami Nakanishi (Auteur), Kazuomi Nakamura (Auteur), Miho Yoshida Yamakawa (Auteur), Hiroyuki Hosokawa (Auteur), Tetsuya Ohbayashi (Auteur), Mitsuo Oshimura (Auteur), Kenji Nakashima (Auteur)
Formaat:	Boek
Gepubliceerd in:	Elsevier, 2015-01-01T00:00:00Z.
Onderwerpen:	article
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